Susceptibility of Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni to florfenicol in Europe, US and Canada

Summary

This systematic review provides the most up-to-date information available in the scientific literature regarding susceptibility to florfenicol of M. haemolytica, P. multocida, and H. somni recently isolated from cattle in Europe, USA and Canada. The relatively low prevalence of Pasteurellaceae resistant to florfenicol indicates that genes conferring resistance to florfenicol such as floR or fexA are not widely distributed among Pasteurellaceae originating from cattle and that new mechanism of resistances to florfenicol are probably slow to develop.